Injectable corticosteroid potency chart

Prednisone is a drug that belongs to the corticosteroid drug class, and is an anti-inflammatory and immune system suppressant. It's used to treat a variety of diseases and conditions, for example: inflammatory bowel disease (Crohn's disease and ulcerative colitis), lupus, asthma, cancers, and several types of arthritis.

Common side effects are weight gain, headache, fluid retention, and muscle weakness. Other effects and adverse events include glaucoma, cataracts, obesity, facial hair growth, moon face, and growth retardation in children. This medicine also causes psychiatric problems, for example: depression, insomnia, mood swings, personality changes, and psychotic behavior. Serious side effects include reactions to diabetes drugs, infections, and necrosis of the hips and joints.

Corticosteroids like prednisone, have many drug interactions; examples include: estrogens, phenytoin (Dilantin), diuretics, warfarin (Coumadin, Jantoven), and diabetes drugs. Prednisone is available as tablets of 1, , 10, 20, and 50 mg; extended release tablets of 1, 2, and 5mg; and oral solution of 5mg/5ml. It's use during the first trimester of pregnancy may cause cleft palate. This medicine is secreted in breast milk and can cause side effects in infants who are nursing. You should not stop taking prednisone abruptly because it can cause withdrawal symptoms and adrenal failure. Talk with your doctor, pharmacist, or other medical professional if you have questions about beta-blockers. Talk with your doctor, pharmacist, or other medical professional if you have questions about prednisone.

If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

IT SHOULD BE EMPHASIZED THAT DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE INDIVIDUALIZED ON THE BASIS OF THE DISEASE UNDER TREATMENT AND THE RESPONSE OF THE PATIENT. After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached. Situations which may make dosage adjustments necessary are changes in clinical status secondary to remissions or exacerbations in the disease process, the patient’s individual drug responsiveness, and the effect of patient exposure to stressful situations not directly related to the disease entity under treatment. In this latter situation it may be necessary to increase the dosage of the corticosteroid for a period of time consistent with the patient’s condition. If after long-term therapy the drug is to be stopped, it is recommended that it be withdrawn gradually rather than abruptly.

1 mg/kg IV every 8 to 12 hours for 1 to 5 days has been studied in premature and term neonates (combined n from 3 studies = 89, gestational age 23 to 40 weeks). An initial loading dose of 2 mg/kg IV was used in 1 retrospective study and another prospective, observational study used a higher maintenance dose of 3 to 6 mg/kg/day IV divided 2 to 4 times daily in a small number of patients (n = 5) with severe capillary leak syndrome and/or previous steroid treatment. In the largest prospective, randomized, placebo controlled study (n = 48, gestational age to weeks), patients receiving hydrocortisone 1 mg/kg IV every 8 hours for 5 days required significantly less vasopressor support (lower doses of dopamine and dobutamine, shorter duration of vasopressor therapy, and fewer patients requiring more than 1 vasopressor) compared to patients receiving placebo. The trend of the average mean arterial blood pressure (MAP) was also significantly higher in patients receiving hydrocortisone compared to patients receiving placebo.

For the pet owner, a serious discussion with your dog's vet is critical in understanding proper use of prednisone and its possible side effects. The list is long and one has to weigh the possible results against the possible side effects. In the past, it was the pet owner's insistence on immediate relief of symptoms that made prednisone the drug of choice for anti-inflammatory action. Today's pet owners are better educated and wiser about long term issues that can be detrimental. Other drugs and treatment options make it possible to alleviate symptoms in the mildly allergic dog without resorting to steroid treatment and should be tried for a period of weeks, even months, before giving up. These options would include a better understanding of day to day attention to environmental factors, improved diet that will build up immunity and often the simple matter of keeping the dog inside in an air conditioned environment during seasonal allergic reactions. When steroid treatment is absolutely needed, the sooner the drug regimen can be completed the better. While steroids may alleviate symptoms, they are not a cure.

Injectable corticosteroid potency chart

injectable corticosteroid potency chart

For the pet owner, a serious discussion with your dog's vet is critical in understanding proper use of prednisone and its possible side effects. The list is long and one has to weigh the possible results against the possible side effects. In the past, it was the pet owner's insistence on immediate relief of symptoms that made prednisone the drug of choice for anti-inflammatory action. Today's pet owners are better educated and wiser about long term issues that can be detrimental. Other drugs and treatment options make it possible to alleviate symptoms in the mildly allergic dog without resorting to steroid treatment and should be tried for a period of weeks, even months, before giving up. These options would include a better understanding of day to day attention to environmental factors, improved diet that will build up immunity and often the simple matter of keeping the dog inside in an air conditioned environment during seasonal allergic reactions. When steroid treatment is absolutely needed, the sooner the drug regimen can be completed the better. While steroids may alleviate symptoms, they are not a cure.

Media:

injectable corticosteroid potency chartinjectable corticosteroid potency chartinjectable corticosteroid potency chartinjectable corticosteroid potency chartinjectable corticosteroid potency chart